1. Which of the following is not a common trait of EDS?
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Joint hypermobility
Skin hyperextensibility
Tissue fragility
Collagen deposits
2. Which type of EDS doesn't currently have genetic testing available?
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hEDS
vEDS
kEDS
cvEDS
3. There's robust evidence to suggest a relationship between EDS and what mental health condition?
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Depression
Anxiety
Post-traumatic stress disorder
Bipolar disorder
4. True or False: Proper medical nutrition therapy can treat EDS and put it into remission.
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True
False
5. Nutritional goals in the setting of EDS focus on adequacy because:
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Most people with EDS have restrictive eating disorders
Eating enough reduces co-occurring abdominal pain
Proper nutrition is needed to maintain the body's physical integrity
Eating too little triggers development of POTS and MCAS
6. Which of the following best describes Mast Cell Activation Syndrome (MCAS)?
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A genetic condition in which mast cells are completely absent from body tissues
A disorder characterized by inappropriate and excessive activation of mast cells leading to recurrent multisystem symptoms
A disease caused by overproduction of histamine from the stomach lining
An autoimmune disease targeting mast cell receptors
7. Which of the following criteria is required to diagnose MCAS?
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Presence of elevated tryptase in urine after a flare
A positive skin-prick test to multiple food allergens
Elevated eosinophil counts on a complete blood count
A positive antinuclear antibody (ANA) test
8. Which of the following specialists is most likely to be involved in the multidisciplinary management of a patient with MCAS?
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Hematologist, allergist/immunologist, gastroenterologist, and dietitian
Dermatologist, ophthalmologist, and speech-language pathologist
Endocrinologist, nephrologist, and podiatrist
Cardiologist, pulmonologist, and orthopedic surgeon
9. What is considered first-line pharmacologic therapy for MCAS?
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Antihistamines targeting both H1 and H2 receptors
Corticosteroids and biologics
Proton pump inhibitors and antibiotics
Immunosuppressants such as methotrexate
10. Which of the following is a common trigger for mast cell activation in MCAS?
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High-fiber foods and gentle exercise
Heat, stress, certain medications, and high-histamine foods
Low-fat diets and hydration
Iron supplementation and sunlight exposure
11. Which of the following diagnostic criteria is required to confirm Postural Orthostatic Tachycardia Syndrome (POTS)?
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Heart rate increase ≥ 20 beats per minute upon standing
Heart rate increase ≥ 30 beats per minute within 10 minutes of standing, without orthostatic hypotension
Drop in systolic blood pressure ≥ 20 mmHg when standing
Heart rate increase ≥ 40 beats per minute regardless of age
12. Which of the following symptoms is most commonly reported among individuals with POTS?
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Increased appetite
Constipation
Lightheadedness, fatigue, and brain fog
Chronic cough and wheezing
13. What percentage of POTS patients are estimated to experience gastrointestinal symptoms such as nausea, bloating, or abdominal pain?
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25–50%
60–70%
90% or more
Less than 10%
14. Which of the following nutrition recommendations is most appropriate for a client with POTS?
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High-fiber, low-sodium diet
2–3 liters of fluids and 4–6 grams of sodium per day
Strict gluten-free diet for all patients
Limit sodium intake to prevent hypertension
15. True or False: POTS should not be diagnosed in a patient who is currently malnourished because cardiac findings related to malnutrition can mimic POTS.
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True
False
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